SCRAPIE USA

Transmissible Spongiform Encephalopathy TSE Prion PrP sheep and goats

My Photo
Name:
Location: BACLIFF, Texas, United States

My mother was murdered by what I call corporate and political homicide i.e. FOR PROFIT! she died from a rare phenotype of CJD i.e. the Heidenhain Variant of Creutzfeldt Jakob Disease i.e. sporadic, simply meaning from unknown route and source. I have simply been trying to validate her death DOD 12/14/97 with the truth. There is a route, and there is a source. There are many here in the USA. WE must make CJD and all human TSE, of all age groups 'reportable' Nationally and Internationally, with a written CJD questionnaire asking real questions pertaining to route and source of this agent. Friendly fire has the potential to play a huge role in the continued transmission of this agent via the medical, dental, and surgical arena. We must not flounder any longer. ...TSS

Saturday, December 08, 2007

SCRAPIE HB Parry Seriously’ (YB88/6.8/4.1)

Saturday, December 08, 2007 SCRAPIE HB Parry Seriously’ (YB88/6.8/4.1)

HB Parry Seriously’ (YB88/6.8/4.1)

IF the scrapie agent is generated from ovine DNA and thence causes disease in other species, then perhaps, bearing in mind the possible role of scrapie in CJD of humans (Davinpour et al, 1985), scrapie and not BSE should be the notifiable disease.

http://www.bseinquiry.gov.uk/files/yb/1988/06/08004001.pdf


1: Neuroepidemiology. 1985;4(4):240-9.

Sheep consumption: a possible source of spongiform encephalopathy in humans.

Davanipour Z, Alter M, Sobel E, Callahan M.

A fatal spongiform encephalopathy of sheep and goats (scrapie) shares many characteristics with Creutzfeldt-Jakob disease (CJD), a similar dementing illness of humans. To investigate the possibility that CJD is acquired by ingestion of contaminated sheep products, we collected information on production, slaughtering practices, and marketing of sheep in Pennsylvania. The study revealed that sheep were usually marketed before central nervous system signs of scrapie are expected to appear; breeds known to be susceptible to the disease were the most common breeds raised in the area; sheep were imported from other states including those with a high frequency of scrapie; use of veterinary services on the sheep farms investigated and, hence, opportunities to detect the disease were limited; sheep producers in the area knew little about scrapie despite the fact that the disease has been reported in the area, and animal organs including sheep organs were sometimes included in processed food. Therefore, it was concluded that in Pennsylvania there are some 'weak links' through which scrapie-infected animals could contaminate human food, and that consumption of these foods could perhaps account for spongiform encephalopathy in humans. The weak links observed are probably not unique to Pennsylvania.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3915057&dopt=Abstract


J Infect Dis 1980 Aug;142(2):205-8

Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates.

Gibbs CJ Jr, Amyx HL, Bacote A, Masters CL, Gajdusek DC.

Kuru and Creutzfeldt-Jakob disease of humans and scrapie disease of sheep and goats were transmitted to squirrel monkeys (Saimiri sciureus) that were exposed to the infectious agents only by their nonforced consumption of known infectious tissues. The asymptomatic incubation period in the one monkey exposed to the virus of kuru was 36 months; that in the two monkeys exposed to the virus of Creutzfeldt-Jakob disease was 23 and 27 months, respectively; and that in the two monkeys exposed to the virus of scrapie was 25 and 32 months, respectively. Careful physical examination of the buccal cavities of all of the monkeys failed to reveal signs or oral lesions. One additional monkey similarly exposed to kuru has remained asymptomatic during the 39 months that it has been under observation.

PMID: 6997404

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6997404&dopt=Abstract


STATEMENT OF DR HELEN GRANT MD FRCP ISSUED 13/05/1999

BSE INQUIRY

http://www.bseinquiry.gov.uk/files/ws/s410.pdf


UNCONVENTIONAL VIRUSES AND THE ORIGIN

AND DISAPPEARANCE OF KURU

Nobel Lecture, December 13, 1976

by D. CARLETON GAJDUSEK

National Institutes of Health, Bethesda, Maryland, U.S.A.

snip...

In a study in Israel, an

overall prevalence in Jews of Libyan origin is 30 times as high as in Jews of

European origin (40). The custom of eating the eyeballs and brains of sheep

in the Jewish households of North African and Middle Eastern origin, as opposed

to Jewish households of European origin, has understandably given rise to the

conjecture that scrapie-infected sheep tissue might be the source of such CJD

infection (37).

SNIP...

The passage of sheep scrapie into other sheep and into goats, at least by the

route of feeding of material contaminated with placenta and embryonic

membrane (53), and into mink from feeding carcasses of scrapied sheep, are

established paths of scrapie transmission. In view of the experimental transmission

of scrapie to monkeys, there is serious cause for wonder whether kitchen

and butchery accidents involving the contamination of skin and eyes may not

be a possible source of CJD in man (36a, 37).

SNIP...

Scrapie has been transmitted in our laboratory to five species of monkeys (Tables 9 and 10) (23, 31, 32), and such transmission has occurred using infected brain from naturally infected sheep and from experimentally infected goats and mice (Figures
22a, b, c). The disease produced is clinically and pathologically indistinguishable
from experimental CJD in these species. .........

Figure 22. Scrapie has been transmitted to three species of New World monkeys and two
species of Old World monkeys (Tables 9, 10). 22a. Transmission of scrapie from the brain of a scrapie-infected Suffolk ewe (C506) in Illinois to a cynomolgus monkey, and from the 4th mouse passage of this strain of scrapie virus to two squirrel monkeys. Incubation period in the cynomolgus was 73 months and in the squirrel monkeys 31 and 33 months. A chimpanzee and a rhesus monkey inoculated 109 months ago with this sheep brain remain well, as does a spider monkey inoculated 70 months ago with brain from the 4th passage of the C506 strain of scrapie in mice.

SNIP...

22b. Primary transmission of goat-adapted scrapie (Compton, England strain) to the
squirrel monkey and to mice and the transmission of mouse-adapted scrapie to two species of Old World and three species of New World monkeys. Numbers in parentheses are the number of months elapsed since inoculation, during which the animal remained asymptomatic.

SNIP...

22c. Transmission of mouse-adapted sheep scrapie (U. S. strain 434-3-897) to a squirrel monkey 38 months following intracerebral inoculation with a suspension of scrapie-infected mouse brain containing 10a7.3 infectious units of virus per ml. This animal showed signs of ataxia, tremors and incoordination, and the disease was confirmed histologically. See (b) for an explanation of symbols.

SNIP...

Figure 23. Transmissible mink encephalopathy (TME), a rare disease of American ranch
mink, is possibly a form of scrapie. The clinical picture and histopathological lesions attendant in the brain, resemble that of scrapie, and scrapie sheep carcasses were fed to mink on ranches on which TME appeared. The disease is transmissible to sheep, goats, certain rodents and New and Old World monkeys. Illustrative data on the primary transmissions of transmissible mink encephalopathy to one species of New World monkey and two species of Old World monkeys, and serial passage of the virus in squirrel, rhesus and stumptailed monkeys are presented in this Figure. Incubation periods are shown in months that elapsed between inoculation and onset of clinical disease. (Figure includes information from our laboratory and from R. F. Marsh, R. J. Eckroade, and R. P. Hanson.)

SNIP... end

SOURCE;

UNCONVENTIONAL VIRUSES AND THE ORIGIN

AND DISAPPEARANCE OF KURU

Nobel Lecture, December 13, 1976

by D. CARLETON GAJDUSEK

National Institutes of Health, Bethesda, Maryland, U.S.A.

Nature. 1972 Mar 10;236(5341):73-4.

Transmission of scrapie to the cynomolgus monkey (Macaca fascicularis). Gibbs CJ Jr, Gajdusek DC. ====================================

Proposed link between transmissible spongiform encephalopathies of man and animals.

Diringer H.

Robert Koch-Institut, Berlin, Germany.

A link between scrapie and Creutzfeldt-Jakob disease (CJD) is likely to exist. Based on old observations on scrapie, new experiments on bovine spongiform encephalopathy, and modern reviews on CJD, my proposal fits general rules of virus transmission

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7475665&dopt=Abstract


Additional Comments

63. I could perhaps sum up MAFF’s approach to BSE with an observation which is by no means original:

“Absence of evidence” is not the same as “evidence of absence”

http://www.bseinquiry.gov.uk/files/ws/s067.pdf


“Absence of evidence” is not the same as “evidence of absence”

I think this might pertain to USDA et al on BSE, BASE, Scrapie's and the Nor-98, CWD, and TME, and human TSE therefrom. ...

TSS

SCRAPIE USA

http://scrapie-usa.blogspot.com/


NOR-98 ATYPICAL SCRAPIE CASES USA

http://nor-98.blogspot.com/


DECLARATION OF EXTRAORDINARY EMERGENCY BECAUSE OF AN ATYPICAL T.S.E. (PRION DISEASE) OF FOREIGN ORIGIN IN THE UNITED STATES [Docket No. 00-072-1]

http://foiamadsheepmadrivervalley.blogspot.com/


CREUTZFELDT JAKOB DISEASE MAD COW BASE UPDATE USA

http://cjdmadcowbaseoct2007.blogspot.com/


Transmissible Mink Encephalopathy TME

http://transmissible-mink-encephalopathy.blogspot.com/


CHRONIC WASTING DISEASE

http://chronic-wasting-disease.blogspot.com/


Monitoring the occurrence of emerging forms of Creutzfeldt-Jakob disease in the United States

http://cjdusa.blogspot.com/


CJD QUESTIONNAIRE

http://cjdquestionnaire.blogspot.com/


CJD TSE NEWS

http://disc.yourwebapps.com/Indices/236650.html


TSS

0 Comments:

Post a Comment

Subscribe to Post Comments [Atom]

<< Home