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Location: BACLIFF, Texas, United States

My mother was murdered by what I call corporate and political homicide i.e. FOR PROFIT! she died from a rare phenotype of CJD i.e. the Heidenhain Variant of Creutzfeldt Jakob Disease i.e. sporadic, simply meaning from unknown route and source. I have simply been trying to validate her death DOD 12/14/97 with the truth. There is a route, and there is a source. There are many here in the USA. WE must make CJD and all human TSE, of all age groups 'reportable' Nationally and Internationally, with a written CJD questionnaire asking real questions pertaining to route and source of this agent. Friendly fire has the potential to play a huge role in the continued transmission of this agent via the medical, dental, and surgical arena. We must not flounder any longer. ...TSS

Friday, April 24, 2015

The placenta shed from goats with classical scrapie is infectious to goat kids and lambs

The placenta shed from goats with classical scrapie is infectious to goat kids and lambs

 

David A. Schneider, D.V.M., Ph.D. (das@vetmed.wsu.edu)1, Sally A. Madsen-Bouterse, Ph.D.2, Dongyue Zhuang3, Thomas C. Truscott4, Rohana P. Dassanayake, Ph.D.5 and Katherine I. O'Rourke, Ph.D.6

 

+ Author Affiliations 1 Animal Disease Research Unit, Agricultural Research Service, U.S. Department of Agriculture 2 Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University 3 Animal Disease Research Unit, Agricultural Research Service, U.S. Department of Agriculture 4 Animal Disease Research Unit, Agricultural Research Service, U.S. Department of Agriculture 5 Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University 6 Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University Received 5 March 2015. Revised 9 April 2015. Accepted 14 April 2015.

 

Abstract

 

The placenta of domestic sheep plays a key role in horizontal transmission of classical scrapie. Domestic goats are frequently raised with sheep and are susceptible to classical scrapie, yet potential routes of transmission from goats to sheep are not fully defined. Sparse accumulation of disease-associated prion protein in cotyledons casts doubt about the role of the goat's placenta. Thus, relevant to mixed-herd management and scrapie-eradication efforts worldwide, we determined if the goat's placenta contains prions orally infectious to goat kids and lambs. A pooled cotyledon homogenate, prepared from the shed placenta of a goat with naturally acquired classical scrapie disease, was used to orally inoculate scrapie-naïve prion genotype-matched goat kids and scrapie-susceptible lambs raised separately in a scrapie-free environment. Transmission was detected in all four goats and in two of four sheep which importantly identifies the goat's placenta as a risk for horizontal transmission to sheep and other goats.

 

snip...

 

In conclusion, this study importantly demonstrates that the placenta of goats infected with classical scrapie can transmit scrapie to susceptible goat kids and lambs via a natural route of exposure despite relatively sparse accumulation of PrPSc 179 within the goat’s placenta. Thus, like for sheep, the parturient materials and postpartum period of goats must be considered transmission risks for other susceptible small ruminants and environmental contamination.

 


 

Sunday, August 25, 2013

 

Prion2013 Chronic Wasting Disease CWD risk factors, humans, domestic cats, blood, and mother to offspring transmission

 


 

>>> Here, in an experimental model of CWD, we have demonstrated the transmission of infectious prions from clinical and subclinical mothers to full-term viable, nonviable and in utero harvested offspring, revealing that the transmission of TSEs from mother to offspring can occur and may be underestimated for all prion diseases. <<<

 

Tuesday, September 17, 2013

 

Mother to Offspring Transmission of Transmissible Spongiform Encephalopathy TSE prion disease

 


 

Wednesday, April 22, 2015

 

Circulation of prions within dust on a scrapie affected farm

 


 

 

TSS

 

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